2011年1月26日 星期三

The truth, the whole truth and nothing but truth?


Happy New Year!  Wish every reader tranquility in 2011.

In the first few days of 2011, I read an advertisement in the newspaper condemning how western medicine could not solve many medical problems.  In the same advertisement, the author claimed that he was able to do so by some methods invented by his good self.  It is now a trend that some individuals, without any formal medical training, be it western or any traditional, claim that they by some unknown reasons, or by self study, find out the reasons of many illnesses and how they can be treated and prevented.  Sometimes they have publications to support their claims, but most, if not all of them, are in the form of books or interviews not scrutinized by others.  The contents of such publications are mainly case reports and circular logics.

Appraisal of evidence needs training.  The public needs to be informed of and educated on these kinds of pseudo-evidence.  I am not saying which tradition of medicine is preferred.  It is the practitioners claiming superiority over others, but without any sound theory or evidence to support them, who are problematic.  Don’t think that many people know about evidence-based medicine and can put it into practice.  I had, in an occasion of a meeting, encountered a doctor who always claimed that he was evidenced-based oriented.  I challenged that the results of a study might not be valid, or at least not accounted for solely by one of the interventions, as there were multiple interventions involved.  To my astonishment, his counter-argument was the promotion of some sort of “black-box theory”.  He claimed that the interventions could be regarded as a black-box.  By all means, as long as it was effective, there was no need for us to bother what happened in between.  I stopped arguing back, as I found it meaningless.  If this “black-box theory” was promoted and preferred, we might be still at the stage of witch doctors.  We need to chant and dance together with our prescription or surgery as we are not sure what actually cause healing.

Sometimes, even the gold standard can be with fault and fraud.  In the January 5, 2011 issue of the British Medical Journal, the journalist Brian Deer wrote about the “MMR vaccine and autism” scam.  In the BMJ Blog, Deer compared this with the “Piltdown Man”: On 21 November 1953, what is now Britain’s Natural History Museum stunned both science and the public by calling the fraud in the case of Piltdown Man.  Fragments of fossilized jaw, skull, and tooth, unearthed shortly before World War I from gravel beds, 45 miles south of London, were not, as had been believed, the remains of an aberrant part-human, part-ape missing link.  They were an elaborate, highly motivated hoax.”  The MMR scam began with a press conference in 1998 after the Lancet published a paper by Andrew Wakefield and colleagues describing 12 children with brain and bowel disease.  “Published in a five-page Lancet paper in February 1998, it triggered media campaigns which sent vaccination rates plummeting, and caused the most intractable health alarm in a generation.  The paper claimed that in two thirds of 12 consecutive child patients with regressive developmental disorder and enterocolitis, attending one London hospital’s paediatric gastroentreology clinic, the apparent precipitating event was a measles, mumps, and rubella vaccine, with a temporal link between shot and symptoms of 14 days.”  Deer cast doubt at the beginning: “Did the scientific community ever really believe that 12 families had turned up consecutively at one hospital, with no reputation for developmental disorders, and made the same highly specific allegations – with a time-link of just days – and that there was not something fishy going on?”  He looked into this matter with his critical mind and diligence.  In 2004, he published his investigation report in Sunday Times and that led to a GMC hearing of the doctors involved.  The hearing lasted 217 days from July 2007 to May 2010.

Deer spent seven years to investigate into Wakefield’s work.  It led to the UK General Medical Council’s longest ever fitness to practise hearing, after which Wakefield and his senior co-author, John Walker-Smith, were struck off the Register.  The paper was also retracted by Lancet.  After GMC published the hearing findings, Deer kept on looking into this matter.  He matched the subjects mentioned to that of the original paper and interviewed their parents.  He concluded that all data had been grossly modified or fabricated.  Apart from having no ground to link MMR vaccine with autism, the whole study was a scam to launch lawsuit against the vaccine manufacturers.  However, as Deer stated: Wakefield, nevertheless, now apparently self-employed and professionally ruined, remains championed by a sad rump of disciples.”  That might reflect how the general public approaches evidence.

Talking about truth seeking, I would like to gladly introduce a new featured writer for the News.  She is Eve LAI and she starts a new regular section about food beginning this issue.  I would describe Eve as a doctor out of my imagination: Like Deer, she exercises her diligence in dissecting myths to expose the truth.  However, her scope only covers food and nothing else.  I am sure that she would present to you, in my opinions, fully biased self experience on food.

Talking about food and truth, I have the duty to report to members my bad (yes, bad; very bad) dining experience at our Central Club House.  I have to blame myself as I have forgotten that the contract of the chef is going to end.  I would advise and remind myself to think three times before choosing the Central Club House again, especially when there are guests and during these few months.  If Central is chosen because of the location, McDonald’s is definitely a better choice.


(Source: HKMA News January 2011)